Email this article 
UJI AKTIVITAS ANTIOKSIDAN DARI EKSTRAK DAUN Tilia kiusiana (Antioxidant Activity Assay of Tilia kiusiana Leaf Extract)
Abstract
There are many of the world’s biodiversity has not been evaluated for any biological activity. To explore the pharmacological potency of nature, the present study investigated antioxidant activity assay of Tilia kiusiana, a Japanese lime tree. Methanolic leaf extract of T. kiusiana was used to analyze the antioxidant assays. The result showed that the extract had moderate activity on antioxidant assays such as DPPH radical scavenging activity (IC50 232.76±1.13µg/mL), reducing power (53.33±1.57 mg QE/g dry extract); hydrogen peroxide (304.49±4.57 µg/mL), and β-karoten (45.80±1.68 µg/mL). The Total Phenolic Content (TPC) revealed that the extract had low values for gallic acid, quercetin, and rutin equivalents (49.29±3.82 mg QE/g dry extract; 36.57±3.01 mg QE/g dry extract; 90.44±7.23 mg QE/g dry extract, respectively). In conclusion, the present study supported the investigation on discovery and resupply of pharmacological active plant-derived natural products.
Keywords
Full Text:
PDFReferences
Basma A. A., Zakaria Z., Lactha Y. L., & Sasidharan S. (2011). Antioxidant Activity and Phytochemical Screening of The Methanol Extracts of Euphorbi hirta L. Asian Pasific Journal of Tropical Medicine, 386-390.
Brahmachari G. (2012). Natural Products in Drug Discovery: Impacts and Opportunities – an Assesment. In Bioactive Natural Products: Opportunities and Challenges in Medicinal Chemistry, 1st Ed., Ed., G. Brahmachari, World Scientific Publisher, Singapore, 1-199.
Cai Y., Luo Q., Sun M., & Corke H. (2004). Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer. Life Science, 74, 2157-2184.
Ebrahimzadeh M. A., Nabavi S. M., Nabavi S. F., Bahramian F., Bekhradnia A. R. 2010. Antioxidant and Free Radical Scavenging Activity of H.Officinalis L. var. Angustifolius, V. Odorata, B.Hyrcana, and C.Speciosum. Pak.J.Pharm.Sci., Vol 23 (1). pp. 29-34.
El-Haci I. A., Bekkara F. A., Mazari W., & Gherib M. (2013). Phenolics content and antioxidant activity of some organic extracts of endemic medicinal plant Anabis aretioides Coss. And Moq. From Algerian Sahara, Pharmacognosy Journal, 5, 108-112.
Gurnani N., Mehta D., Gupta M., & Mehta B. K. (2014). Natural Products: Source of Potential Drugs. African Journal of Basic & Applied Sciences, 6(6), 171-186.
Harvey A. L. (2008). Natural product in drug discovery. Drug Discovery Today, 13(19/20), 894-901.
Jayaprakasha G. K., Singh R. P., & Sakariah K. K. (2001). Antioxidant activity of grape seed (Vitis vinifera) extracts on peroxidation models in vitro. Food Chemistry, 73,285-290.
Li Y.Q., Zhou F.C., Gao F., Bian J.S & Shan F. (2009). Comparative evaluation of quercetin, Isoquercetin and rutin as inhibitor of α-glucosidase. Journal of Agricultural and Food Chemistry, 57,11463-11468.
Newman D. J. & Cragg G. M. (2016). Natural Products as Sources of New Drugs from 1981 to 2014, Journal of Natural Products, 79, 629-661.
Ortholand J. Y & Ganesan A. (2004). Natural products and combinatorial chemistry: back to the future. Current Opinion in Clinical Biology, 8,271-280.
Pattrick, Graham. (2001). Medicinal chemistry. BIOS Scientific publisher. UK.
Prihantini A. I., Tachibana S., & Itoh K. (2014). Evaluation of Antioksidant and α–Glucosidase Inhibitory Activities of Some Subtropical Plants. Pakistan Journal of Biological Sciences, 17(10), 1106-1114.
Ruch R. J., Cheng S. J., & Klavning J. E. (1989). Prevention of cytotoxicity and inhibition of intracellular communication by antioxidant catechins isolated from Chinese green tea. Carcinogens, 10,1003-1008.
Sajeeth C.I., Manna P.K., Manavalan R., Jolly C.I. (2010). Quantitative estimation of gallic acid, rutin and quercetin in certain herbal plants by HPTLC method. Der Chemica Sinica, 1,80-85.
Singleton V. L., Orthofer R., & Raventos R. M. L. (1999). Analysis of total phenols and other oxidation substrates and antioxidant by means of Folin-Ciocalteu reagent. Methods in Enzymology, 299,152-178.
Tadera K., Minami Y., Takamatsu K., Matsuoka T. (2006). Inhibition of α-glucosidase and α-amylase by flavonoids. Journal of Nutritional Science and Vitaminology, 52,149-153.
Yen G. C. & Chen H. Y. (1995). Antioxidant activity of various tea extracts in relation to their antimutagenicity. Journal of Agriculture and Food Chemistry, 43,27-32.
DOI: https://doi.org/10.20886/jpkf.2017.1.2.59-66
Refbacks
- There are currently no refbacks.
Copyright©2018 | Jurnal Penelitian Kehutanan Faloak (JPKF)
eISSN : 2579-5805, pISSN : 2620-617X
JPKF is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Jurnal Penelitian Kehutanan FALOAK indexed By:
